Pre-Employment Testing

Pre-Employment DOT Drug Test for CDL Drivers

Most CDL drivers need a verified negative DOT pre-employment drug test result and a clean Clearinghouse query before operating a commercial motor vehicle.

Last updated: May 2026

When CDL drivers need a pre-employment drug test

A pre-employment DOT drug test is generally required before a covered driver first performs a safety-sensitive function. This applies to new hires at trucking companies and to owner-operators who are starting under their own DOT authority.

Owner-operator pre-employment testing

When you start operating under your own authority, you are effectively your own first hire. You typically need a verified negative DOT pre-employment drug test on file. We schedule the collection and provide the documentation.

New driver onboarding for fleets

Before letting a new driver get behind the wheel, fleets must collect a negative DOT pre-employment test result and run a full FMCSA Clearinghouse query. Our team coordinates both pieces for you.

What happens before the driver can operate

  • Driver reports to a DOT-certified collection site
  • 5-panel DOT urine collection performed
  • Lab analyzes the specimen
  • Medical Review Officer (MRO) reviews and verifies the result
  • Negative result is released to the employer / C/TPA
  • Clearinghouse query is completed

How to schedule a collection

Submit the form below with the driver's information. We send the collection paperwork (chain of custody) and point you to the nearest DOT-certified collection site. Most drivers can be tested the same or next business day.

How this connects to the Clearinghouse

A pre-employment drug test alone is not enough. Employers must also run a full FMCSA Clearinghouse pre-employment query to check for prior drug and alcohol program violations.

Schedule a Pre-Employment DOT Drug Test

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Frequently Asked Questions

Ready to get your DOT drug testing program set up?

Enroll today or talk to us about your fleet. We help owner-operators and small trucking companies get set up quickly.